

Traveling in a northeast-to-southwest alignment in a valley through mostly farmland and some woodlands, the Interstate has its first interchange with State Route 341 (SR 341) a short distance later near White Pine. I-81 begins at a directional T interchange with I-40 near Dandridge in unincorporated Jefferson County about 35 miles (56 km) east of downtown Knoxville. In 2022, annual average daily traffic (AADT) volumes ranged from 61,299 vehicles per day at the southern terminus to 34,896 vehicles per day between US 25E and SR 160. I-81 is maintained by the Tennessee Department of Transportation (TDOT), along with all other Interstate, US, and state highways in Tennessee. Route description I-81 northbound at the SR 394 exit in Blountville From 1985 to 2007, the Interstate had one auxiliary route, I-181, which was renumbered as part of I-26. The last stretch of I-81 in Tennessee, which was more than half of the entire route in the state, was completed in 1975. However, most of the route was constructed later than the other Interstate Highways initially allocated to Tennessee, and did not open until after 1970. The first parts of I-81 in the state were constructed in the early 1960s, with additional progress made on the Interstate throughout that decade. Numbered Highway until it reaches Bristol. Routes 11E and 11W in Tennessee, but unlike many stretches of Interstate Highways, does not closely parallel any U.S. I-81 roughly follows the corridors of U.S. It remains in the Ridge-and-Valley topographic region of the Appalachian Mountains for its entire length in Tennessee, and runs in a northeast to southwest direction. I-81 bypasses most cities that it serves, instead providing access via interchanges with state and federal routes. The route serves the Tri-Cities region of the state and the eastern parts of the Knoxville metropolitan area, terminating about 35 miles (56 km) east of Knoxville. In Tennessee, I-81 serves the northeastern part of the state, running 75.66 miles (121.76 km) from its southern terminus with I-40 in Dandridge to the Virginia state line in Bristol. Interstate 81 ( I-81) is part of the Interstate Highway System that runs 855.02 miles (1,376.02 km) northward from Dandridge, Tennessee, to the Thousand Islands Bridge at the Canadian border near Fishers Landing, New York. Jefferson, Hamblen, Greene, Washington, Sullivan I-81 at the Virginia state line in Bristol
